@Article{info:doi/10.2196/70129, author="Zhao, Yi and Zhong, Yi and Xiong, Mengqi and Huang, Linlin and Ye, Xiujin and He, Jingsong", title="Incidence, Prognostic Factors, and Treatment Impact on Survival in Natural Killer/T-Cell Lymphoma: Population-Based Study in the United States", journal="JMIR Form Res", year="2025", month="May", day="15", volume="9", pages="e70129", keywords="NK/T-cell lymphoma", keywords="incidence", keywords="prognostic factors", keywords="chemoradiotherapy", keywords="SEER", abstract="Background: Natural killer/T-cell lymphoma (NKTL) is a rare malignancy of mature natural killer/T-cells, predominantly found in Asian and South/Central American populations, with limited studies conducted in Europe and the United States. Objective: The aim of this study is to present an overview of the incidence rate, demographic and clinical characteristics, treatment options, overall survival (OS), and factors influencing OS of NKTL in the United States. Methods: We used data from the Surveillance, Epidemiology, and End Results 17 database to analyze NKTL cases recorded between 2000 and 2020. In a cohort of 1162 patients with NKTL, we calculated the incidence rates and performed statistical analyses to evaluate OS, the effect of radiotherapy and chemotherapy on survival, and lymphoma-specific survival. Results: The mean annual incidence rate of NKTL in the United States was 0.067 per 100,000, with higher rates observed in men compared to women, and an increase noted with age. However, there has been no significant rise in incidence over recent years. Significant racial disparities were observed, with higher incidence rates in non-Hispanic Asian or Pacific Islanders and Hispanic people. The median survival time for patients with NKTL was 21 months, with a 5-year OS rate of 39.5\%, which has shown improvement in recent years. Key independent prognostic factors impacting patient survival included age at diagnosis, clinical stage, nasal type presentation, presence of systemic symptoms, and treatment modality. Patients receiving combined radiotherapy and chemotherapy exhibited the best outcomes, with a median OS of 138 months and a 5-year OS rate of 58\%. This survival benefit remained consistent even in patients with stage I/localized nasal type lymphoma, achieving a 5-year OS rate of 73.3\%. Conclusions: The incidence of NKTL has remained stable in recent years. Patients with the nasal type generally experience better survival outcomes. The use of combined radiotherapy and chemotherapy appears to enhance survival, though further validation through prospective multicenter clinical trials is necessary. ", doi="10.2196/70129", url="https://formative.jmir.org/2025/1/e70129" } @Article{info:doi/10.2196/53335, author="Schubert, Cicero Marc and Soyka, Stella and Wick, Wolfgang and Venkataramani, Varun", title="Guideline-Incorporated Large Language Model-Driven Evaluation of Medical Records Using MedCheckLLM", journal="JMIR Form Res", year="2025", month="Apr", day="24", volume="9", pages="e53335", keywords="large language models", keywords="AI", keywords="electron medical records", keywords="checklists", keywords="LLM", keywords="language model", keywords="NLP", keywords="natural language processing", keywords="records", keywords="documentation", keywords="documents", keywords="framework", keywords="conceptual", keywords="machine learning", keywords="artificial intelligence", keywords="evidence", keywords="evaluate", keywords="evaluation", keywords="guideline", keywords="health care", abstract="Abstract: The study introduces MedCheckLLM, a large language model--driven framework that enhances medical record evaluation through a guideline-in-the-loop approach by integrating evidence-based guidelines. ", doi="10.2196/53335", url="https://formative.jmir.org/2025/1/e53335" } @Article{info:doi/10.2196/68105, author="Cook, Nicole and Biel, M. Frances and Bet, Ann Kerry and Sills, R. Marion and Al Bataineh, Ali and Rivera, Pedro and Templeton, R. Anna and Cartwright, Natalie", title="Engaging Stakeholders With Professional or Lived Experience to Improve Firearm Violence Lexicon Development", journal="JMIR Form Res", year="2025", month="Apr", day="21", volume="9", pages="e68105", keywords="firearm violence", keywords="firearm injury", keywords="stakeholder engagement", keywords="natural language processing", keywords="electronic health record", doi="10.2196/68105", url="https://formative.jmir.org/2025/1/e68105" } @Article{info:doi/10.2196/58366, author="Ghossein, Jamie and Hryciw, N. Brett and Ramsay, Tim and Kyeremanteng, Kwadwo", title="The AI Reviewer: Evaluating AI's Role in Citation Screening for Streamlined Systematic Reviews", journal="JMIR Form Res", year="2025", month="Mar", day="28", volume="9", pages="e58366", keywords="article screening", keywords="artificial intelligence", keywords="systematic review", keywords="AI", keywords="large language model", keywords="LLM", keywords="screening", keywords="analysis", keywords="reviewer", keywords="app", keywords="ChatGPT 3.5", keywords="chatbot", keywords="dataset", keywords="data", keywords="adoption", doi="10.2196/58366", url="https://formative.jmir.org/2025/1/e58366" } @Article{info:doi/10.2196/50536, author="Kautsar, Prawira Angga and Sinuraya, Kurnia Rano and van der Schans, Jurjen and Postma, Jacobus Maarten and Suwantika, A. Auliya", title="Exploring Public Sentiment on the Repurposing of Ivermectin for COVID-19 Treatment: Cross-Sectional Study Using Twitter Data", journal="JMIR Form Res", year="2025", month="Mar", day="27", volume="9", pages="e50536", keywords="COVID-19", keywords="ivermectin", keywords="sentiment analysis", keywords="Twitter", keywords="social media", keywords="public health", keywords="misinformation", keywords="geolocation analysis", doi="10.2196/50536", url="https://formative.jmir.org/2025/1/e50536" } @Article{info:doi/10.2196/64085, author="Rajamani, Sripriya and Austin, Robin and Richwine, Chelsea and Britt-Lalich, Malin and Thakur, Madhur and Odowa, Yasmin and Jantraporn, Ratchada and Marquard, Jenna", title="Understanding Patient Portal Uses and Needs: Cross-Sectional Study in a State Fair Setting", journal="JMIR Form Res", year="2024", month="Oct", day="11", volume="8", pages="e64085", keywords="patient portals", keywords="patient engagement", keywords="health information technology", keywords="consumer health informatics", keywords="health informatics", keywords="use", keywords="online access", keywords="medical records", keywords="data access", keywords="functionality", doi="10.2196/64085", url="https://formative.jmir.org/2024/1/e64085" } @Article{info:doi/10.2196/63858, author="Wisniewski, Payson and Depuy, Julia and Kim, Cassandra and Garrison, Olivia and Jerome, J. Gerald", title="Supporting Weight Loss Among Parents of Children With a Disability: Lessons Learned From a Single-Arm Pilot Study", journal="JMIR Form Res", year="2024", month="Oct", day="7", volume="8", pages="e63858", keywords="weight loss", keywords="obesity", keywords="disability", keywords="parent", keywords="family", keywords="child", keywords="weight loss intervention", doi="10.2196/63858", url="https://formative.jmir.org/2024/1/e63858", url="http://www.ncbi.nlm.nih.gov/pubmed/39374058" } @Article{info:doi/10.2196/55577, author="Zhang, Boyan and Du, Yueqi and Duan, Wanru and Chen, Zan", title="Benchmarking Large Language Models for Cervical Spondylosis", journal="JMIR Form Res", year="2024", month="Aug", day="5", volume="8", pages="e55577", keywords="cervical spondylosis", keywords="large language model", keywords="LLM", keywords="patient", keywords="ChatGPT", doi="10.2196/55577", url="https://formative.jmir.org/2024/1/e55577" } @Article{info:doi/10.2196/58263, author="Bravata, Dena and Russell, Daniel and Fellows, Annette and Goldman, Ron and Pace, Elizabeth", title="Digitally Enabled Peer Support and Social Health Platform for Vulnerable Adults With Loneliness and Symptomatic Mental Illness: Cohort Analysis", journal="JMIR Form Res", year="2024", month="Jul", day="24", volume="8", pages="e58263", keywords="peer support", keywords="social isolation", keywords="loneliness", keywords="depression", keywords="depressive", keywords="mental health", keywords="anxiety", keywords="quality of life", keywords="isolation", keywords="isolated", keywords="online support", keywords="digital health", keywords="vulnerable", keywords="race", keywords="racial ethnic", keywords="ethnicity", keywords="gender", keywords="socioeconomic", keywords="demographic", doi="10.2196/58263", url="https://formative.jmir.org/2024/1/e58263", url="http://www.ncbi.nlm.nih.gov/pubmed/38941568" } @Article{info:doi/10.2196/56165, author="Dagli, Marcel Mert and Oettl, Conrad Felix and Gujral, Jaskeerat and Malhotra, Kashish and Ghenbot, Yohannes and Yoon, W. Jang and Ozturk, K. Ali and Welch, C. William", title="Clinical Accuracy, Relevance, Clarity, and Emotional Sensitivity of Large Language Models to Surgical Patient Questions: Cross-Sectional Study", journal="JMIR Form Res", year="2024", month="Jun", day="7", volume="8", pages="e56165", keywords="artificial intelligence", keywords="AI", keywords="natural language processing", keywords="NLP", keywords="large language model", keywords="LLM", keywords="generative AI", keywords="cross-sectional study", keywords="health information", keywords="patient education", keywords="clinical accuracy", keywords="emotional sensitivity", keywords="surgical patient", keywords="surgery", keywords="surgical", doi="10.2196/56165", url="https://formative.jmir.org/2024/1/e56165", url="http://www.ncbi.nlm.nih.gov/pubmed/38848553" } @Article{info:doi/10.2196/55202, author="Baus, Adam and Boatman, D. Dannell and Calkins, Andrea and Pollard, Cecil and Conn, Ellen Mary and Subramanian, Sujha and Kennedy-Rea, Stephenie", title="A Health Information Technology Protocol to Enhance Colorectal Cancer Screening", journal="JMIR Form Res", year="2024", month="Apr", day="19", volume="8", pages="e55202", keywords="electronic health record", keywords="EHR", keywords="colorectal cancer screening", keywords="health information technology", keywords="cancer", keywords="colorectal cancer", doi="10.2196/55202", url="https://formative.jmir.org/2024/1/e55202", url="http://www.ncbi.nlm.nih.gov/pubmed/38640474" } @Article{info:doi/10.2196/51249, author="van Alen, Marie Catharina and Brenner, Alexander and Warnecke, Tobias and Varghese, Julian", title="Smartwatch Versus Routine Tremor Documentation: Descriptive Comparison", journal="JMIR Form Res", year="2024", month="Mar", day="20", volume="8", pages="e51249", keywords="Parkinson disease", keywords="tremor", keywords="smart wearables", keywords="smartwatch", keywords="mobile apps", keywords="movement disorders", keywords="tremor documentation", keywords="tremor occurrence", keywords="tremor score", doi="10.2196/51249", url="https://formative.jmir.org/2024/1/e51249", url="http://www.ncbi.nlm.nih.gov/pubmed/38506919" } @Article{info:doi/10.2196/54632, author="Jones, Grant and Herrmann, Felipe and Bear, Adam and Carhart-Harris, Robin and Kettner, Hannes", title="The Relationship Between Changes in Mindfulness and Subsequent Changes in Well-Being Following Psychedelic Use: Prospective Cohort Study", journal="JMIR Form Res", year="2024", month="Mar", day="4", volume="8", pages="e54632", keywords="psychedelics", keywords="mindfulness", keywords="observational", keywords="web-based survey", keywords="psychedelic", keywords="meditation", keywords="mental health", keywords="anxiety", keywords="depression", keywords="survey", keywords="surveys", keywords="drug", keywords="drugs", keywords="substance use", keywords="hallucinogen", keywords="hallucinogens", doi="10.2196/54632", url="https://formative.jmir.org/2024/1/e54632", url="http://www.ncbi.nlm.nih.gov/pubmed/38437005" }